Integrated Facility for Macromolecular Crystallography
We maintain this state-of-the-art facility in collaboration with the laboratory of Prof. Chris Ulens. The facility was established in 2009-2010 through to a grant from the Hercules Foundation. Crystallization setups are done with a Mosquito crystallization robot and subsequently observed using two automated crystallization imagers (RockImager) at 4 and 20 °C with web access. Diffraction data collection is carried out using a Rigaku 007 X-ray source with HF optics, Mar345 image plate detector and an Oxford Cryosystems 700 series cryojet (see photo below).
- Wet laboratory fully equipped for molecular cloning, recombinant protein expression in E.coli and protein purification
- Two temperature-stabilized rooms at 4 and 20 °C for crystallization equipped with stereomicroscopes
- Crystallographic computing cluster including stereo graphics and a recently added (2016) 28-core node
Research collaborations: please feel free to contact us if you are interested in using any of the abovementioned equipment.